BOTH 2',3'-DIDEOXYTHYMIDINE AND ITS 2',3'-UNSATURATED DERIVATIVE (2',3'-DI-DEOXYTHYMIDINENE) ARE POTENT AND SELECTIVE INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS-REPLICATION INVITRO

被引：347

作者：

BABA, M

PAUWELS, R

HERDEWIJN, P

DECLERCQ, E

DESMYTER, J

VANDEPUTTE, M

机构：

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1987年 / 142卷 / 01期

关键词：

D O I：

10.1016/0006-291X(87)90460-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：128 / 134

页数：7

共 11 条

[1] POTENT AND SELECTIVE ANTI-HTLV-III/LAV ACTIVITY OF 2',3'-DIDEOXYCYTIDINENE, THE 2',3'-UNSATURATED DERIVATIVE OF 2',3'-DIDEOXYCYTIDINE [J].

BALZARINI, J ;

PAUWELS, R ;

HERDEWIJN, P ;

DECLERCQ, E ;

COONEY, DA ;

KANG, GJ ;

DALAL, M ;

JOHNS, DG ;

BRODER, S .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1986, 140 (02) :735-742

[2] ISOLATION OF A T-LYMPHOTROPIC RETROVIRUS FROM A PATIENT AT RISK FOR ACQUIRED IMMUNE-DEFICIENCY SYNDROME (AIDS) [J].

BARRESINOUSSI, F ;

CHERMANN, JC ;

REY, F ;

NUGEYRE, MT ;

CHAMARET, S ;

GRUEST, J ;

DAUGUET, C ;

AXLERBLIN, C ;

VEZINETBRUN, F ;

ROUZIOUX, C ;

ROZENBAUM, W ;

MONTAGNIER, L .

SCIENCE, 1983, 220 (4599) :868-871

[3] A PATHOGENIC RETROVIRUS (HTLV-III) LINKED TO AIDS [J].

BRODER, S ;

GALLO, RC .

NEW ENGLAND JOURNAL OF MEDICINE, 1984, 311 (20) :1292-1297

[4] CHEMOTHERAPEUTIC APPROACHES TO THE TREATMENT OF THE ACQUIRED-IMMUNE-DEFICIENCY-SYNDROME (AIDS) [J].

DECLERCQ, E .

JOURNAL OF MEDICINAL CHEMISTRY, 1986, 29 (09) :1561-1569

[5] ISOLATION OF HUMAN T-CELL LEUKEMIA-VIRUS IN ACQUIRED IMMUNE-DEFICIENCY SYNDROME (AIDS) [J].

GALLO, RC ;

SARIN, PS ;

GELMANN, EP ;

ROBERTGUROFF, M ;

RICHARDSON, E ;

KALYANARAMAN, VS ;

MANN, D ;

SIDHU, GD ;

STAHL, RE ;

ZOLLAPAZNER, S ;

LEIBOWITCH, J ;

POPOVIC, M .

SCIENCE, 1983, 220 (4599) :865-867

[6] INFECTION OF HTLV-III/LAV IN HTLV-I-CARRYING CELLS MT-2 AND MT-4 AND APPLICATION IN A PLAQUE-ASSAY [J].

HARADA, S ;

KOYANAGI, Y ;

YAMAMOTO, N .

SCIENCE, 1985, 229 (4713) :563-566

[7] INHIBITION OF THE INVITRO INFECTIVITY AND CYTOPATHIC EFFECT OF HUMAN LYMPHOTROPHIC-T VIRUS "TYPE-III/LYMPHADENOPATHY-ASSOCIATED VIRUS (HTLV-III/LAV) BY 2',3'-DIDEOXYNUCLEOSIDES [J].

MITSUYA, H ;

BRODER, S .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (06) :1911-1915

[8] 3'-AZIDO-3'-DEOXYTHYMIDINE (BW A509U) - AN ANTIVIRAL AGENT THAT INHIBITS THE INFECTIVITY AND CYTOPATHIC EFFECT OF HUMAN LYMPHOTROPIC-T VIRUS TYPE-III LYMPHADENOPATHY-ASSOCIATED VIRUS INVITRO [J].

MITSUYA, H ;

WEINHOLD, KJ ;

FURMAN, PA ;

STCLAIR, MH ;

LEHRMAN, SN ;

GALLO, RC ;

BOLOGNESI, D ;

BARRY, DW ;

BRODER, S .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (20) :7096-7100

[9]

PAUWELS R, 1986, UNPUB

[10] DETECTION, ISOLATION, AND CONTINUOUS PRODUCTION OF CYTOPATHIC RETROVIRUSES (HTLV-III) FROM PATIENTS WITH AIDS AND PRE-AIDS [J].

POPOVIC, M ;

SARNGADHARAN, MG ;

READ, E ;

GALLO, RC .

SCIENCE, 1984, 224 (4648) :497-500

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