CHIRAL PHARMACEUTICALS - SCALE-UP, CONTROL AND ITS SIGNIFICANCE FOR DRUG RESEARCH

被引：6

作者：

FEDERSEL, HJ

机构：

来源：

CHEMIE IN UNSERER ZEIT | 1993年 / 27卷 / 02期

关键词：

D O I：

10.1002/ciuz.19930270205

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

收藏

页码：78 / 87

页数：10

相关论文

共 49 条

[1]

Allenmark S. G., 1988, CHROMATOGRAPHIC ENAN

[2] STEREOCHEMISTRY, A BASIS FOR SOPHISTICATED NONSENSE IN PHARMACOKINETICS AND CLINICAL-PHARMACOLOGY [J].

ARIENS, EJ .

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 1984, 26 (06) :663-668

[3] RACEMIC MIXTURES AND SINGLE STEREOISOMERS - INDUSTRIAL CONCERNS AND ISSUES IN DRUG DEVELOPMENT [J].

CAYEN, MN .

CHIRALITY, 1991, 3 (02) :94-98

[4]

Collins A. N., 1992, CHIRALITY IND THE CO

[5] SYNTHETIC ENZYMES .4. HIGHLY ENANTIOSELECTIVE EPOXIDATION BY MEANS OF POLYAMINOACIDS IN A TRIPHASE SYSTEM - INFLUENCE OF STRUCTURAL VARIATIONS WITHIN THE CATALYSTS [J].

COLONNA, S ;

MOLINARI, H ;

BANFI, S ;

JULIA, S ;

MASANA, J ;

ALVAREZ, A .

TETRAHEDRON, 1983, 39 (09) :1635-1641

[6] ON THE ORIGIN OF ENANTIOSELECTIVITY IN THE KATSUKI-SHARPLESS EPOXIDATION PROCEDURE [J].

COREY, EJ .

JOURNAL OF ORGANIC CHEMISTRY, 1990, 55 (06) :1693-1694

[7] SYNTHESIS OF OPTICALLY-ACTIVE COMPOUNDS - A LARGE-SCALE PERSPECTIVE [J].

CROSBY, J .

TETRAHEDRON, 1991, 47 (27) :4789-4846

[8] THE RELEVANCE OF CHIRALITY TO THE STUDY OF BIOLOGICAL-ACTIVITY [J].

CROSSLEY, R .

TETRAHEDRON, 1992, 48 (38) :8155-8178

[9] THE FDA PERSPECTIVE ON THE DEVELOPMENT OF STEREOISOMERS [J].

DECAMP, WH .

CHIRALITY, 1989, 1 (01) :2-6

[10] SEPARATION OF AMINO-ACID ENANTIOMERS AND CHIRAL AMINES USING PRECOLUMN DERIVATIZATION WITH (+)-1-(9-FLUORENYL)ETHYL CHLOROFORMATE AND REVERSED-PHASE LIQUID-CHROMATOGRAPHY [J].

EINARSSON, S ;

JOSEFSSON, B ;

MOLLER, P ;

SANCHEZ, D .

ANALYTICAL CHEMISTRY, 1987, 59 (08) :1191-1195

← 1 2 3 4 5 →