A POTENTIOMETRIC, SPECTROPHOTOMETRIC AND H-1-NMR STUDY ON THE INTERACTION OF CIMETIDINE, FAMOTIDINE AND RANITIDINE WITH PLATINUM(II) AND PALLADIUM(II) METAL-IONS

被引：31

作者：

CRISPONI, G

CRISTIANI, F

NURCHI, VM

SILVAGNI, R

GANADU, ML

LUBINU, G

NALDINI, L

PANZANELLI, A

机构：

[1] UNIV SASSARI,DIPARTIMENTO CHIM,I-07100 SASSARI,ITALY

[2] UNIV CAGLIARI,DIPARTIMENTO CHIM & TECNOL INORGAN & MET ORGA,I-09124 CAGLIARI,ITALY

来源：

POLYHEDRON | 1995年 / 14卷 / 11期

关键词：

D O I：

10.1016/0277-5387(94)00379-S

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Spectrophotometric, potentiometric and H-1 NMR results on the M-L systems [M = Pd-II or Pt-II and L = cimetidine, famotidine or ranitidine] are clearly indicative of the strong chelating ability of these antiulcerative drugs towards metal ions. In view of the great biological interest in these two metals, their coordination to such drugs should have significant implications.

引用

页码：1517 / 1530

页数：14

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