PREGNANCY OUTCOME IN RENAL-ALLOGRAFT RECIPIENTS - INFLUENCE OF CYCLOSPORINE-A

被引：26

作者：

HAUGEN, G

FAUCHALD, P

SODAL, G

HALVORSEN, S

OLDEREID, N

MOE, N

机构：

[1] NATL HOSP NORWAY,DEPT OBSTET & GYNECOL,OSLO 1,NORWAY

[2] NATL HOSP NORWAY,DEPT INTERNAL MED,OSLO 1,NORWAY

[3] NATL HOSP NORWAY,DEPT SURG,OSLO 1,NORWAY

[4] ULLEVAL HOSP,DEPT INTERNAL MED,OSLO 1,NORWAY

来源：

EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY | 1991年 / 39卷 / 01期

关键词：

PREGNANCY; RENAL TRANSPLANTATION; CICLOSPORIN-A;

D O I：

10.1016/0028-2243(91)90137-A

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The outcome of 35 pregnancies in 26 renal allograft recipients is reported. Twenty-four pregnancies in patients treated with prednisolone and azathioprine resulted in 22 live-born infants (one twin pregnancy) and 3 induced abortions on medical indications. Three of the deliveries were preterm, and one of the infants had a birth weight below the 2.5th percentile. Ten patients (11 pregnancies) were treated with ciclosporin A (CsA). These women delivered 5 infants (3 preterm deliveries of whom the birth weight of one infant was below the 5th percentile) and underwent 3 induced (medical indications) and 3 spontaneous abortions. Mean birth weight in the CsA treated group was 2464 g (range 1790-2930 g), and their gestational age varied from 232 to 271 days. No foetal malformations were observed in the two groups. The results may indicate a harmful effect of CsA on pregnancy outcome.

引用

页码：25 / 29

页数：5

共 19 条

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