ASYMMETRIC-SYNTHESIS OF EXO-NORBORNANE-2-CARBOXYLIC ACIDS

被引：7

作者：

AVENOZA, A ^{[1
]}

BUENO, MP ^{[1
]}

CATIVIELA, C ^{[1
]}

MAYORAL, JA ^{[1
]}

机构：

[1] COLEGIO UNIV LA RIOJA,DEPT QUIM ORGAN,E-26001 LOGRONO,SPAIN

来源：

TETRAHEDRON-ASYMMETRY | 1992年 / 3卷 / 03期

关键词：

D O I：

10.1016/S0957-4166(00)80270-0

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The reaction between N-acryloyl-N-methyl-L-alanine methyl ester and cyclopentadiene is studied. The configuration of the cycloadducts preferably obtained depends on the reaction conditions and the Lewis acid used as a catalyst. In TiCl4-catalyzed reactions, high exo:endo ratios and good diastereomeric excesses in exo cycloadducts are obtained under several conditions. So an interesting method for the asymmetric synthesis of derivatives of exo-norbornane-2-carboxylic acid is described.

引用

页码：343 / 346

页数：4

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