BENEFICIAL-EFFECTS OF ELECTROMAGNETIC-FIELDS

被引:187
作者
BASSETT, CAL
机构
[1] Bioelectric Research Center, Columbia University, Riverdale, New York
关键词
CELL FUNCTION; MAGNETIC FIELDS; PEMF; CONNECTIVE TISSUES; MUSCULOSKELETAL DISORDERS;
D O I
10.1002/jcb.2400510402
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Selective control of cell function by applying specifically configured, weak, time-varying magnetic fields has added a new, exciting dimension to biology and medicine. Field parameters for therapeutic, pulsed electromagnetic field (PEMFs) were designed to induce voltages similar to those produced, normally, during dynamic mechanical deformation of connective tissues. As a result, a wide variety of challenging musculoskeletal disorders have been treated successfully over the past two decades. More than a quarter million patients with chronically ununited fractures have benefitted, worldwide, from this surgically non-invasive method, without risk, discomfort, or the high costs of operative repair. Many of the athermal bioresponses, at the cellular and subcellular levels, have been identified and found appropriate to correct or modify the pathologic processes for which PEMFs have been used. Not only is efficacy supported by these basic studies but by a number of double-blind trials. As understanding of mechanisms expands, specific requirements for field energetics are being defined and the range of treatable ills broadened. These include nerve regeneration, wound healing, graft behavior; diabetes, and myocardial and cerebral ischemia (heart attack and stroke), among other conditions. Preliminary data even suggest possible benefits in controlling malignancy.
引用
收藏
页码:387 / 393
页数:7
相关论文
共 25 条
[1]  
BASSETT CAL, 1974, SCIENCE, V184, P575
[2]   GENERATION OF ELECTRIC POTENTIALS BY BONE IN RESPONSE TO MECHANICAL STRESS [J].
BASSETT, CAL ;
BECKER, RO .
SCIENCE, 1962, 137 (3535) :1063-&
[3]  
BASSETT CAL, 1989, CRIT REV BIOMED ENG, V17, P451
[4]   ACCELERATION OF FRACTURE REPAIR BY ELECTROMAGNETIC-FIELDS - SURGICALLY NONINVASIVE METHOD [J].
BASSETT, CAL ;
PAWLUK, RJ ;
PILLA, AA .
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1974, 238 (OCT11) :242-262
[5]  
BASSETT CAL, 1971, BIOCH PHYSL BONE, P1
[6]  
BASSETT CAL, 1993, BIOL EFFECTS MAGNETI
[7]  
BASSETT LS, 1979, ELECTRICAL PROPERTIE, P311
[8]   SENSITIVITY OF CALCIUM-BINDING IN CEREBRAL TISSUE TO WEAK ENVIRONMENTAL ELECTRIC-FIELDS OSCILLATING AT LOW-FREQUENCY [J].
BAWIN, SM ;
ADEY, WR .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1976, 73 (06) :1999-2003
[9]  
BLANK M, 1992, 1ST P WORLD C EL MAG
[10]  
DELOOF A, 1986, INT REV CYTOL, V104, P251