OXAZOLINE-MEDIATED BIARYL COUPLING REACTIONS - STEREOCONTROLLED SYNTHESIS OF 2,2',6,6'-TETRASUBSTITUTED BIPHENYLS

被引：41

作者：

MOORLAG, H ^{[1
]}

MEYERS, AI ^{[1
]}

机构：

[1] COLORADO STATE UNIV,DEPT CHEM,FT COLLINS,CO 80523

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 44期

关键词：

D O I：

10.1016/S0040-4039(00)61578-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

High diastereoselectivities (93:7) were observed in the biaryl coupling of 2',6'-disubstituted aryl Grignard reagents of 1 with aryloxazolines 2. The diasteroselectivities observed in the coupling reaction varied primarily as a function of the chelating properties of the ortho substituents on the aryl Grignard reagent.

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页码：6989 / 6992

页数：4

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