(ACYLOXY)ALKYL CARBAMATES AS NOVEL BIOREVERSIBLE PRODRUGS FOR AMINES - INCREASED PERMEATION THROUGH BIOLOGICAL-MEMBRANES

被引：75

作者：

ALEXANDER, J ^{[1
]}

CARGILL, R ^{[1
]}

MICHELSON, SR ^{[1
]}

SCHWAM, H ^{[1
]}

机构：

[1] MERCK SHARP & DOHME RES LABS, W POINT, PA 19486 USA

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1988年 / 31卷 / 02期

关键词：

D O I：

10.1021/jm00397a008

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

收藏

页码：318 / 322

页数：5

相关论文

共 49 条

[1] ALEXANDER J, 1893, Patent No. 507316
[2] ALEXANDER J, Patent No. 167451
[3] ALEXANDER J, 1885, Patent No. 327156
[4] ALEXANDER J, Patent No. 130119
[5] AVRAM M, 1972, INFRARED SPECTROSCOP, P467
[6] N-HYDROXYMETHYL DERIVATIVES OF NITROGEN-HETEROCYCLES AS POSSIBLE PRODRUGS .2. POSSIBLE PRODRUGS OF ALLOPURINOL, GLUTETHIMIDE, AND PHENOBARBITAL
BANSAL, PC
PITMAN, IH
HIGUCHI, T
[J]. JOURNAL OF PHARMACEUTICAL SCIENCES, 1981, 70 (08) : 855 - 857
[7] THERMODYNAMICS OF PARTITIONING OF BETA-BLOCKERS IN THE NORMAL-OCTANOL-BUFFER AND LIPOSOME SYSTEMS
BETAGERI, GV
ROGERS, JA
[J]. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1987, 36 (2-3) : 165 - 173
[8] BODOR N, 1980, Journal of Medicinal Chemistry, V23, P469, DOI 10.1021/jm00179a001
[9] BODOR N, 1982, A BENZON S, V17, P156
[10] PRODRUGS AS DRUG DELIVERY SYSTEMS .4. N-MANNICH BASES AS POTENTIAL NOVEL PRODRUGS FOR AMIDES, UREIDES, AMINES, AND OTHER NH-ACIDIC COMPOUNDS
BUNDGAARD, H
JOHANSEN, M
[J]. JOURNAL OF PHARMACEUTICAL SCIENCES, 1980, 69 (01) : 44 - 46

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