ORAL BIOAVAILABILITY AND INTRAVENOUS PHARMACOKINETICS OF AMRINONE IN HUMANS

被引：26

作者：

PARK, GB

KERSHNER, RP

ANGELLOTTI, J

WILLIAMS, RL

BENET, LZ

EDELSON, J

机构：

[1] STERLING WINTHROP RES INST, DEPT DRUG METAB, RENSSELAER, NY 12144 USA

[2] UNIV CALIF SAN FRANCISCO, DRUG STUDIES UNIT, SAN FRANCISCO, CA 94143 USA

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 1983年 / 72卷 / 07期

关键词：

D O I：

10.1002/jps.2600720726

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：817 / 819

页数：3

共 12 条

[1] CARDIOTONIC ACTIVITY OF AMRINONE-WIN 40680 [5-AMINO-3,4'-BIPYRIDIN-6(1H)-ONE] [J].

ALOUSI, AA ;

FARAH, AE ;

LESHER, GY ;

OPALKA, CJ .

CIRCULATION RESEARCH, 1979, 45 (05) :666-677

[2]

ALOUSI AA, 1978, FED PROC, V37, P914

[3]

ALOUSI AA, 1981, PHARM BIOCH PROPERTI, V3, P120

[4] EFFECTS OF AMRINONE ON MYOCARDIAL ENERGY-METABOLISM AND HEMODYNAMICS IN PATIENTS WITH SEVERE CONGESTIVE HEART-FAILURE DUE TO CORONARY-ARTERY DISEASE [J].

BENOTTI, JR ;

GROSSMAN, W ;

BRAUNWALD, E ;

CARABELLO, BA .

CIRCULATION, 1980, 62 (01) :28-34

[5] HEMODYNAMIC ASSESSMENT OF AMRINONE - NEW INOTROPIC AGENT [J].

BENOTTI, JR ;

GROSSMAN, W ;

BRAUNWALD, E ;

DAVOLOS, DD ;

ALOUSI, AA .

NEW ENGLAND JOURNAL OF MEDICINE, 1978, 299 (25) :1373-1377

[6] RELATIONSHIP BETWEEN AMRINONE PLASMA-CONCENTRATION AND CARDIAC INDEX [J].

EDELSON, J ;

LEJEMTEL, TH ;

ALOUSI, AA ;

BIDDLECOME, CE ;

MASKIN, CS ;

SONNENBLICK, EH .

CLINICAL PHARMACOLOGY & THERAPEUTICS, 1981, 29 (06) :723-728

[7] NEW CARDIOTONIC AGENTS - SEARCH FOR DIGITALIS SUBSTITUTE [J].

FARAH, AE ;

ALOUSI, AA .

LIFE SCIENCES, 1978, 22 (13-1) :1139-1147

[8]

HELWIG JT, 1979, SAS USERS GUIDE, P317

[9] AMRINONE METABOLISM [J].

KULLBERG, MP ;

FREEMAN, GB ;

BIDDLECOME, C ;

ALOUSI, AA ;

EDELSON, J .

CLINICAL PHARMACOLOGY & THERAPEUTICS, 1981, 29 (03) :394-401

[10] HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC ANALYSIS OF AMRINONE AND ITS N-ACETYL DERIVATIVE IN PLASMA - PHARMACOKINETICS OF AMRINONE IN THE DOG [J].

KULLBERG, MP ;

DORRBECKER, B ;

LENNON, J ;

ROWE, E ;

EDELSON, J .

JOURNAL OF CHROMATOGRAPHY, 1980, 187 (01) :264-270

← 1 2 →