ACUTE ANTERIOR UVEITIS, ANKYLOSING-SPONDYLITIS, BACK PAIN, AND HLA-B27

被引:41
作者
BECKINGSALE, AB [1 ]
DAVIES, J [1 ]
GIBSON, JM [1 ]
ROSENTHAL, AR [1 ]
机构
[1] UNIV LEICESTER, SCH MED, DEPT OPHTHALMOL, LEICESTER LE1 7RH, ENGLAND
关键词
D O I
10.1136/bjo.68.10.741
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Patients (169) with acute anterior uveitis were studied for the presence of HLA-B27 tissue type, radiological evidence of ankylosing spondylitis, and a history of back pain, 60% were male; 45% were HLA-B27+. The male:female ratio in the HLA-B27+ group was the same as in the whole group, 24% had radiological evidence of ankylosing spondylitis, and, of these, 83% were HLA-B27 + while 17% were HLA-B27-. There was a definite correlation between the severity of the ankylosing spondylitis and preponderance of males in the HLA-B27+ group of patients. Significant back pain occurred in 60% of HLA-B27+ patients but in only 14% of HLA-B27+ patients. The importance of the selection of patients and of consistency in the use of diagnostic criteria in studies relating to ankylosing spondylitis and acute anterior uveitis is stressed.
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收藏
页码:741 / 745
页数:5
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