CONTINUING CONTROVERSY IN ALLOIMMUNE THROMBOCYTOPENIA - FETAL HYPERIMMUNOGLOBULINEMIA FAILS TO PREVENT THROMBOCYTOPENIA

被引：59

作者：

NICOLINI, U ^{[1
]}

TANNIRANDORN, Y ^{[1
]}

GONZALEZ, P ^{[1
]}

FISK, NM ^{[1
]}

BEACHAM, J ^{[1
]}

LETSKY, EA ^{[1
]}

RODECK, CH ^{[1
]}

机构：

[1] HAMMERSMITH HOSP,DEPT CHEM PATHOL,LONDON W12 0HS,ENGLAND

来源：

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY | 1990年 / 163卷 / 04期

关键词：

Alloimmune thrombocytopenia; intracranial hemorrhage; platelet transfusion;

D O I：

10.1016/0002-9378(90)90674-V

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Two patients with severe alloimmune thrombocytopenia were managed by weekly intrauterine platelet transfusions at 25 to 36 weeks. In one patient high-dose immunoglobulin was also administered weekly to the mother, and high maternal and fetal immunoglobulin levels were achieved. Fetal platelet counts were similar in both patients. The only variable that affected fetal platelet concentration was the posttransfusion platelet count from the previous transfusion. © 1990.

引用

页码：1144 / 1146

页数：3