IDENTIFYING STRATEGIES FOR IMMUNE INTERVENTION

被引:208
作者
LANZAVECCHIA, A
机构
[1] Basel Institute for Immunology
关键词
D O I
10.1126/science.8493532
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
In recent years the molecular basis of antigen recognition by T cells has been unraveled and the various pathways that control T cell activation and functional specialization have been defined. Consequently, it is now possible to delineate various strategies for intervention with the immune system to design protective vaccines, to induce an effective response to tumor antigens, and to control graft rejection and autoimmune diseases.
引用
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页码:937 / 944
页数:8
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