USE OF MICELLAR ELECTROKINETIC CAPILLARY CHROMATOGRAPHY IN THE STUDY OF IN-VITRO METABOLISM OF PHENOL BY HUMAN LIVER-MICROSOMES

被引：6

作者：

DAVIES, MI

LUNTE, CE

SMYTH, MR

机构：

[1] DUBLIN CITY UNIV,SCH CHEM SCI,DUBLIN 9,IRELAND

[2] UNIV KANSAS,DEPT CHEM,LAWRENCE,KS 66045

来源：

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | 1995年 / 13卷 / 07期

关键词：

HUMAN LIVER MICROSOMES; METABOLISM; MICELLAR ELECTROKINETIC CAPILLARY CHROMATOGRAPHY; PHENOL;

D O I：

10.1016/0731-7085(95)01500-K

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Micellar electrokinetic capillary chromatography (MECC) is used for analysis of microsome incubation samples. Phenol, a neutral analyte, is separated form interferences. The separation is achieved without sample clean-up. MECC is shown to be advantageous for situations where rapid sampling with minimum handling is desired.

引用

页码：893 / 897

页数：5

共 10 条

[1]

CADWELL J, 1980, ENZYMATIC BASIS DETO, V1, P85

[2]

COON MJ, 1980, ENZYMATIC BASIS DETO, V1, P117

[3]

GILLETTA JR, 1973, LABORATORY ANIMAL DR, P1

[4] PROTOCOL FOR RESOLVING PROTEIN MIXTURES IN CAPILLARY ZONE ELECTROPHORESIS [J].