ABSENT FACTOR-2 IN SYSTEMIC LUPUS-ERYTHEMATOSUS - IMMUNOLOGICAL STUDIES AND RESPONSE TO CORTICOSTEROID-THERAPY

被引：29

作者：

NATELSON, EA

CYPRUS, GS

HETTIG, RA

机构：

[1] METHODIST HOSP, DEPT INTERN MED, HOUSTON, TX USA

[2] BAYLOR UNIV, COLL MED, DEPT MED, SECT HEMATOL, HOUSTON, TX USA

来源：

ARTHRITIS AND RHEUMATISM | 1976年 / 19卷 / 01期

关键词：

D O I：

10.1002/art.1780190113

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This report describes a patient with active systemic lupus erythematosus (SLE) who evidenced severe bleeding consequent to a profound and isolated reduction in plasma factor II (prothrombin) activity. Absence of the factor is documented by immunologic means; its return after corticosteroid therapy is demonstrated. Inclusion of this acquired coagulopathy among other more traditional diagnostic manifestations of SLE is suggested.

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页码：79 / 82

页数：4

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