LAMININ BINDING-PROTEINS

被引：64

作者：

MERCURIO, AM

SHAW, LM

机构：

[1] Laboratory of Cancer Biology, Deaconess Hospital, Harvard Medical School, Boston, Massachusetts, 02115

来源：

BIOESSAYS | 1991年 / 13卷 / 09期

关键词：

D O I：

10.1002/bies.950130907

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Cells express many proteins that bind to laminin, the major adhesive component of basement membranes. Some of these, specifically integrins, function as transmembrane receptors that 'signal' the presence of laminin on the cell surface to the cytoplasm. Lectins constitute a second class of laminin binding proteins that may augment integrin function by interacting with laminin carbohydrate. Caution must be used in ascribing functions to other laminin binding proteins, especially cytosolic proteins.

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页码：469 / 473

页数：5

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