ASYMMETRIC-SYNTHESIS OF THE C-26-C-32 TETRAHYDROPYRAN MOIETY OF SWINHOLIDE-A BY HETERO-DIELS-ALDER REACTION

被引：22

作者：

MULZER, J ^{[1
]}

MEYER, F ^{[1
]}

BUSCHMANN, J ^{[1
]}

LUGER, P ^{[1
]}

机构：

[1] FREE UNIV BERLIN,INST KRISTALLOG,D-14195 BERLIN,GERMANY

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 20期

关键词：

EXO-SELECTIVE HETERO-DIELS-ALDER REACTION; 4-OXANONES; ANOMERIC EFFECT; LEWIS ACID CATALYSIS; STEREOSELECTIVE CARBONYL REDUCTION;

D O I：

10.1016/0040-4039(95)00576-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A three step stereoselective synthesis of the C-26-C-32 tetrahydropyran section of Swinholide A (1) via a Lewis acid mediated hetero-Diels-Alder reaction is presented.

引用

页码：3503 / 3506

页数：4

共 7 条

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[5] TOTAL SYNTHESIS OF SWINHOLIDE-A AND HEMISWINHOLIDE-A
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[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (20) : 9391 - 9392
[6] THATCHER GRJ, 1993, J AM CHEM SOC, V539
[7] TROST BM, 1991, COMPREHENSIVE ORGANI, V2

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