Screening a 2 cM genetic map for allelic association: A simulated oligogenic trait

被引：6

作者：

Duffy, DL ^{[1
]}

机构：

[1] QUEENSLAND INST MED RES,BRISBANE,QLD 4006,AUSTRALIA

来源：

GENETIC EPIDEMIOLOGY | 1995年 / 12卷 / 06期

关键词：

transmission disequilibrium test;

D O I：

10.1002/gepi.1370120612

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

In this paper, we explore the use of a variety of familial transmission tests (and case-control analyses) to screen for allelic associations in simulated marker data of a quality (2 cM map) that will feasibly arise from genomic scans within the next 5-10 years. We demonstrate a form of the transmission-disequilibrium test extended to multiallele systems. The methods used were log-linear and related models implemented largely using standard statistical packages. (C) 1995 Wiley-Liss, Inc.

引用

页码：595 / 600

页数：6