WHAT HAVE WE LEARNT FROM HYPERBARIC-OXYGEN

被引：37

作者：

DISCHE, S

机构：

[1] Marie Curie Research Wing Regional Centre for Radiotherapy and Oncology, Mount Vernon Hospital, Northwood

来源：

RADIOTHERAPY AND ONCOLOGY | 1991年 / 20卷

关键词：

RADIOTHERAPY; HYPERBARIC OXYGEN; CARBOGEN; TUMOR CONTROL; CLINICAL TRIAL;

D O I：

10.1016/0167-8140(91)90191-I

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The 15 randomised controlled clinical trials of hyperbaric oxygen in radiotherapy yielded three with highly significant benefit and six with useful margins not reaching statistical significance. The increase in tumour control was partly negated by an increase in normal tissue effect. Now simple carbogen breathing in animal tumour models has shown high efficiency and there is the potential for its use in man as a simple means of hypoxic cell radiosensitisation.

引用

页码：71 / 74

页数：4

共 11 条

[1] HYPERBARIC-OXYGEN THERAPY FOR CARCINOMA OF THE CERVIX - STAGE-IIB, STAGE-IIIA, STAGE-IIIB AND STAGE-IVA - RESULTS OF A RANDOMIZED STUDY BY THE RADIATION-THERAPY ONCOLOGY GROUP
BRADY, LW
PLENK, HP
HANLEY, JA
GLASSBURN, JR
KRAMER, S
PARKER, RG
[J]. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1981, 7 (08): : 991 - 998
[2] REDOX COMPETITION AND RADIOSENSITIVITY - IMPLICATIONS FOR TESTING RADIOPROTECTIVE COMPOUNDS
DENEKAMP, J
ROJAS, A
STEVENS, G
[J]. PHARMACOLOGY & THERAPEUTICS, 1988, 39 (1-3) : 59 - 66
[3] DISCHE S, 1983, BIOL BASIS RADIOTHER, P225
[4] DISCHE S, UNPUB INT J RAD ONCO
[5] FLETCHER GH, 1977, CANCER, V39, P617, DOI 10.1002/1097-0142(197702)39:2<617::AID-CNCR2820390237>3.0.CO
[6] 2-2
[7] OXYGEN DISTRIBUTION IN SQUAMOUS-CELL CARCINOMA METASTASES AND ITS RELATIONSHIP TO OUTCOME OF RADIATION-THERAPY
GATENBY, RA
KESSLER, HB
ROSENBLUM, JS
COIA, LR
MOLDOFSKY, PJ
HARTZ, WH
BRODER, GJ
[J]. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1988, 14 (05): : 831 - 838
[8] ROJAS A, 1989, BIR REPORT, V19, P86
[9] SEALY R, 1979, ADV MED ONCOLOGY, V6, P223
[10] THE HISTOLOGICAL STRUCTURE OF SOME HUMAN LUNG CANCERS AND THE POSSIBLE IMPLICATIONS FOR RADIOTHERAPY
THOMLINSON, RH
GRAY, LH
[J]. BRITISH JOURNAL OF CANCER, 1955, 9 (04) : 539 - &

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