LACK OF CORRELATION BETWEEN COLONY MORPHOLOGY AND LIPOOLIGOSACCHARIDE CONTENT IN THE MYCOBACTERIUM-TUBERCULOSIS COMPLEX

被引：26

作者：

LEMASSU, A

LEVYFREBAULT, VV

LANEELLE, MA

DAFFE, M

机构：

[1] CNRS, CTR RECH BIOCHIM & GENET CELLULAIRES, 118 ROUTE NARBONNE, F-31062 TOULOUSE, FRANCE

[2] INST PASTEUR, UNITE TB MYCOBACTERIES, F-75724 PARIS 15, FRANCE

来源：

JOURNAL OF GENERAL MICROBIOLOGY | 1992年 / 138卷

关键词：

D O I：

10.1099/00221287-138-7-1535

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Rough and smooth colony variants of the Mycobacterium tuberculosis complex were compared with respect to their composition in trehalose-containing glycolipid antigens in view of the results of a recent investigation suggesting that the chemical basis of rough and smooth colony morphology in mycobacteria may reside in the occurrence of lipooligosaccharides. A careful chemical characterization of the individual glycolipids of the selected strains allowed the identification of the major glycolipids. The comparative study of the glycolipid content of the smooth Canetti strain, its spontaneous rough variant, and 16 additional strains of M. tuberculosis, M. bovis and M. africanum showed that the presence of lipooligosaccharides was not related to the morphology of the colonies.

引用

页码：1535 / 1541

页数：7

共 33 条

[1] ISOLATION IN HIGH-FREQUENCY OF ROUGH VARIANTS OF MYCOBACTERIUM-INTRACELLULARE LACKING C-MYCOSIDE GLYCOPEPTIDOLIPID ANTIGENS [J].