CAN VARYING FLOW VELOCITY ACROSS AN ARTERIAL ANASTOMOSIS PREVENT THROMBOEMBOLIC INJURY

被引：8

作者：

BARKER, JH

ANDRESEN, DM

ANDERSON, GL

SCHUSCHKE, D

GU, JM

GUPTA, S

HJORTDAL, VE

DERR, JW

BANIS, JC

ACLAND, RD

机构：

[1] Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Louisville, Louisville, Kentucky

来源：

MICROSURGERY | 1995年 / 16卷 / 05期

关键词：

D O I：

10.1002/micr.1920160512

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

In this study, simulated ''poor'' repairs applied to transverse incisions in the iliac arteries of 40 rats were the basis for comparing the effect of variations in blood flow on thromboembolism. Using vital microscopy and digital image processing, we performed 2 experiments. In the first experiment (n = 20), the reduction of post-repair blood flow by approximately 50% resulted in an 83% reduction in the total number of emboli appearing in the microcirculation of the cremaster muscle distal to the repair. In the second experiment (n = 20), the same reduction in blood flow typically resulted in larger repair-site thrombi which required significantly more time to grow to their maximum size. We conclude that reducing pedicle artery blood flow to approximately half in our rat model during reperfusion can protect the downstream microcirculation from embolic injury without increasing the incidence of thrombotic occlusion. (C) 1995 Wiley-Liss, Inc.

引用

页码：349 / 356

页数：8

共 28 条

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