Cardiovascular and metabolic effects of Berberine

被引：99

作者：

Affuso, Flora ^{[1
]}

Mercurio, Valentina ^{[1
]}

Fazio, Valeria ^{[1
]}

Fazio, Serafino ^{[1
]}

机构：

[1] Univ Naples Federico II, Sch Med, Dept Internal Med Cardiovasc & Immunol Sci, Via S Pansini 5, I-80131 Naples, Italy

来源：

WORLD JOURNAL OF CARDIOLOGY | 2010年 / 2卷 / 04期

关键词：

Metabolic syndrome; Berberine; Adenosine monophosphate kinase; Insulin resistance; Hyperlipidemia; Endothelial function;

D O I：

10.4330/wjc.v2.i4.71

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

Berberine (BBR) is a natural alkaloid isolated from the Coptis Chinensis. While this plant has been used in Ayurvedic and Chinese medicine for more than 2500 years, interest in its effects in metabolic and cardiovascular disease has been growing in the Western world in the last decade. Many papers have been published in these years reporting beneficial effects in carbohydrate and lipid metabolism, endothelial function and the cardiovascular system. In this review, we report a detailed analysis of the scientific literature regarding this topic, describing the effects and the underlying mechanisms of BBR on carbohydrate and lipid metabolism, endothelial function and the cardiovascular system. (C) 2010 Baishideng. All rights reserved.

引用

页码：71 / 77

页数：7

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[1]

Extracellular signal-regulated kinase-dependent stabilization of hepatic low-density lipoprotein receptor mRNA by herbal medicine berberine [J].