PHARMACOKINETIC STUDIES ON RO-15-1788, A BENZODIAZEPINE RECEPTOR LIGAND, IN THE BRAIN OF THE RAT

被引：85

作者：

LISTER, RG

GREENBLATT, DJ

ABERNETHY, DR

FILE, SE

机构：

[1] UNIV LONDON,SCH PHARM,DEPT PHARMACOL,LONDON WC1N 1AX,ENGLAND

[2] TUFTS UNIV,NEW ENGLAND MED CTR,DIV CLIN PHARMACOL,BOSTON,MA 02111

来源：

BRAIN RESEARCH | 1984年 / 290卷 / 01期

关键词：

D O I：

10.1016/0006-8993(84)90752-2

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

引用

页码：183 / 186

页数：4

共 13 条

[1] DETERMINATION OF RO-15-1788, A BENZODIAZEPINE ANTAGONIST, IN HUMAN-PLASMA BY GAS-LIQUID-CHROMATOGRAPHY WITH NITROGEN-PHOSPHORUS DETECTION - APPLICATION TO SINGLE-DOSE PHARMACOKINETIC STUDIES [J].

ABERNETHY, DR ;

ARENDT, RM ;

LAUVEN, PM ;

GREENBLATT, DJ .

PHARMACOLOGY, 1983, 26 (05) :285-289

[2] SPECIFIC PROCONVULSANT ACTION OF AN IMIDAZOBENZODIAZEPINE (RO-15-1788) ON ISONIAZID CONVULSIONS [J].

CORDA, MG ;

COSTA, E ;

GUIDOTTI, A .

NEUROPHARMACOLOGY, 1982, 21 (01) :91-94

[3] BEHAVIORAL EVIDENCE FOR PARTIAL AGONIST PROPERTIES OF RO-15-1788, A BENZODIAZEPINE RECEPTOR ANTAGONIST [J].

DANTZER, R ;

PERIO, A .

EUROPEAN JOURNAL OF PHARMACOLOGY, 1982, 81 (04) :655-658

[4] RO 15-1788 ANTAGONIZES THE CENTRAL EFFECTS OF DIAZEPAM IN MAN WITHOUT ALTERING DIAZEPAM BIOAVAILABILITY [J].

DARRAGH, A ;

LAMBE, R ;

KENNY, M ;

BRICK, I ;

TAAFFE, W ;

OBOYLE, C .

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1982, 14 (05) :677-682

[5] LIQUID-CHROMATOGRAPHIC DETERMINATION OF CHLORDIAZEPOXIDE AND METABOLITES IN PLASMA [J].

DIVOLL, M ;

GREENBLATT, DJ ;

SHADER, RI .

PHARMACOLOGY, 1982, 24 (05) :261-266

[6] THE ANXIOGENIC ACTION OF BENZODIAZEPINE ANTAGONISTS [J].

FILE, SE ;

LISTER, RG ;

NUTT, DJ .

NEUROPHARMACOLOGY, 1982, 21 (10) :1033-1037

[7] INTRINSIC ACTIONS OF BENZODIAZEPINE ANTAGONISTS [J].

FILE, SE ;

LISTER, RG ;

NUTT, DJ .

NEUROSCIENCE LETTERS, 1982, 32 (02) :165-168

[8] CONVULSIONS INDUCED BY SUBMAXIMAL DOSE OF PENTYLENETETRAZOL IN MICE ARE ANTAGONIZED BY THE BENZODIAZEPINE ANTAGONIST RO 15-1788 [J].

GRECKSCH, G ;

DECARVALHO, LP ;

VENAULT, P ;

CHAPOUTHIER, G ;

ROSSIER, J .

LIFE SCIENCES, 1983, 32 (22) :2579-2584

[9] SELECTIVE ANTAGONISTS OF BENZODIAZEPINES [J].

HUNKELER, W ;

MOHLER, H ;

PIERI, L ;

POLC, P ;

BONETTI, EP ;

CUMIN, R ;

SCHAFFNER, R ;

HAEFELY, W .

NATURE, 1981, 290 (5806) :514-516

[10]

LISTER RG, J CHROM

← 1 2 →