ISOTOPE EFFECTS ON THE SEQUENCE-SPECIFIC CLEAVAGE OF DC IN D(AGC) SEQUENCES BY NEOCARZINOSTATIN - ELUCIDATION OF CHEMISTRY OF MINOR LESIONS

被引：61

作者：

KAPPEN, LS

GOLDBERG, IH

WU, SH

STUBBE, JA

WORTH, L

KOZARICH, JW

机构：

[1] HARVARD UNIV, SCH MED, DEPT BIOL CHEM & MOLEC PHARMACOL, BOSTON, MA 02115 USA

[2] MIT, DEPT CHEM, CAMBRIDGE, MA 02139 USA

[3] UNIV MARYLAND, CTR AGR BIOTECHNOL, COLLEGE PK, MD 20742 USA

[4] UNIV MARYLAND, DEPT CHEM & BIOCHEM, COLLEGE PK, MD 20742 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1990年 / 112卷 / 07期

关键词：

D O I：

10.1021/ja00163a049

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

[No abstract available]

引用

页码：2797 / 2798

页数：2

共 16 条

[1] SITES IN THE DIYNE ENE BICYCLIC CORE OF NEOCARZINOSTATIN CHROMOPHORE RESPONSIBLE FOR HYDROGEN ABSTRACTION FROM DNA [J].

CHIN, DH ;

ZENG, CH ;

COSTELLO, CE ;

GOLDBERG, IH .

BIOCHEMISTRY, 1988, 27 (21) :8106-8114

[2] THE STRUCTURE OF NEOCARZINOSTATIN CHROMOPHORE POSSESSING A NOVEL BICYCLO-[7,3,0]DODECADIYNE SYSTEM [J].

EDO, K ;

MIZUGAKI, M ;

KOIDE, Y ;

SETO, H ;

FURIHATA, K ;

OTAKE, N ;

ISHIDA, N .

TETRAHEDRON LETTERS, 1985, 26 (03) :331-334

[3] FREE-RADICAL MECHANISMS IN NEOCARZINOSTATIN-INDUCED DNA DAMAGE [J].

GOLDBERG, IH .

FREE RADICAL BIOLOGY AND MEDICINE, 1987, 3 (01) :41-54

[4] NEOCARZINOSTATIN CHROMOPHORE - PRESENCE OF A HIGHLY STRAINED ETHER RING AND ITS REACTION WITH MERCAPTAN AND SODIUM-BOROHYDRIDE [J].

HENSENS, OD ;

DEWEY, RS ;

LIESCH, JM ;

NAPIER, MA ;

REAMER, RA ;

SMITH, JL ;

ALBERSSCHONBERG, G ;

GOLDBERG, IH .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1983, 113 (02) :538-547

[5] CONVERSION OF MONO- AND OLIGODEOXYRIBONUCLEOTIDES TO 5'-TRIPHOSPHATES [J].

HOARD, DE ;

OTT, DG .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1965, 87 (08) :1785-&

[6] ACTIVATION OF NEOCARZINOSTATIN CHROMOPHORE AND FORMATION OF NASCENT DNA DAMAGE DO NOT REQUIRE MOLECULAR-OXYGEN [J].

KAPPEN, LS ;

GOLDBERG, IH .

NUCLEIC ACIDS RESEARCH, 1985, 13 (05) :1637-1648

[7] ATYPICAL ABASIC SITES GENERATED BY NEOCARZINOSTATIN AT SEQUENCE-SPECIFIC CYTIDYLATE RESIDUES IN OLIGODEOXYNUCLEOTIDES [J].

KAPPEN, LS ;

CHEN, CQ ;

GOLDBERG, IH .

BIOCHEMISTRY, 1988, 27 (12) :4331-4340

[8] IDENTIFICATION OF 2-DEOXYRIBONOLACTONE AT THE SITE OF NEOCARZINOSTATIN-INDUCED CYTOSINE RELEASE IN THE SEQUENCE D(AGC) [J].

KAPPEN, LS ;

GOLDBERG, IH .

BIOCHEMISTRY, 1989, 28 (03) :1027-1032

[9] SEQUENCE-SPECIFIC ISOTOPE EFFECTS ON THE CLEAVAGE OF DNA BY BLEOMYCIN [J].

KOZARICH, JW ;

WORTH, L ;

FRANK, BL ;

CHRISTNER, DF ;

VANDERWALL, DE ;

STUBBE, J .

SCIENCE, 1989, 245 (4924) :1396-1399

[10] PROPOSED STRUCTURE OF THE NEOCARZINOSTATIN CHROMOPHORE-METHYL THIOGLYCOLATE ADDUCT - A MECHANISM FOR THE NUCLEOPHILIC ACTIVATION OF NEOCARZINOSTATIN [J].

MYERS, AG .

TETRAHEDRON LETTERS, 1987, 28 (39) :4493-4496

← 1 2 →