IDENTIFICATION OF SIDE-PRODUCTS FORMED BY DERIVATIZATION OF 2-HYDROXYCARBOXYLIC ACIDS WITH METHYL AND ETHYL CHLOROFORMATE

被引：15

作者：

LIEBICH, HM ^{[1
]}

GESELE, E ^{[1
]}

WAHL, HG ^{[1
]}

WIRTH, C ^{[1
]}

WOLL, J ^{[1
]}

HUSEK, P ^{[1
]}

机构：

[1] RES INST ENDOCRINOL, CS-11694 PRAGUE 1, CZECHOSLOVAKIA

来源：

JOURNAL OF CHROMATOGRAPHY | 1992年 / 626卷 / 02期

关键词：

D O I：

10.1016/0021-9673(92)85423-Q

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Derivatization of 2-hydroxycarboxylic acids with methyl and ethyl chloroformate leads to O-alkoxycarbonylalkyl esters. In addition to the main product a number of side-products are formed, which were identified by gas chromatography-mass spectrometry. They include lactides and ''inter-ester'' oligomers with alkoxycarbonyl-derivatized and with underivatized terminal OH group. The ''interesters'' result from the reaction between two, three or four hydroxycarboxylic acid molecules.

引用

页码：289 / 293

页数：5

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