INVESTIGATION OF STEREOSELECTIVITIES IN THE COUPLING REACTIONS OF 1-O-METHYL-3, 5-DI-O-P-TOLUOYL-2-DEOXYRIBOFURANOSIDE WITH PURINES AND PYRIMIDINES

被引：12

作者：

JANARDHANAM, S ^{[1
]}

NAMBIAR, KP ^{[1
]}

机构：

[1] UNIV CALIF DAVIS,DEPT CHEM,DAVIS,CA 95616

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 22期

关键词：

D O I：

10.1016/S0040-4039(00)73064-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Stereoselectivities in the coupling reaction between 1-O-methyl-3,5-di-O-p-toluoyl-2-deoxyribofuranoside and suitably protected purine and pyrimidine derivatives have been examined in acetonitrile with varying equivalents of SnCl4. The best result in alpha-nucleoside formation was obtained when the coupling reaction was carried out in the presence of ten equivalents of SnCl4.

引用

页码：3657 / 3660

页数：4

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