VARIABLE REJECTION PATTERNS OF CULTURED KERATINOCYTE ALLOGRAFTS IN THE RABBIT

被引：5

作者：

BREIDAHL, AF ^{[1
]}

JUDSON, RT ^{[1
]}

DUMBLE, LJ ^{[1
]}

CLUNIE, GJA ^{[1
]}

机构：

[1] UNIV MELBOURNE,ROYAL MELBOURNE HOSP,DEPT SURG,MELBOURNE,VIC 3050,AUSTRALIA

来源：

BRITISH JOURNAL OF PLASTIC SURGERY | 1993年 / 46卷 / 03期

关键词：

D O I：

10.1016/0007-1226(93)90174-A

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

There are many conflicting reports on the survival of cultured keratinocyte allografts (CKAs). Studies were performed in the rabbit model to elucidate further the fate of CKAs. Of 24 CKAs, 7 were identified as technical failures, 13 displayed classical macroscopic evidence of rejection with a prolonged mean survival time of 2.8 days, compared to non-cultured allograft controls (p < 0.01), and 4 failed to display typical macroscopic evidence of rejection. Furthermore, the time to eventual wound healing of the classically rejected CKAs were delayed by 6.0 days (p < 0.0001), compared to identical non-grafted control wounds.

引用

页码：235 / 239

页数：5

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