THE CONVERSION OF N-ACETYLTYRAMINE TO N-ACETYLDOPAMINE BY SCHISTOCERCA-GREGARIA THORACIC GANGLIA

被引：5

作者：

MIR, AK ^{[1
]}

VAUGHAN, PFT ^{[1
]}

机构：

[1] UNIV GLASGOW, DEPT BIOCHEM, GLASGOW G12 8QQ, SCOTLAND

来源：

INSECT BIOCHEMISTRY | 1981年 / 11卷 / 05期

关键词：

D O I：

10.1016/0020-1790(81)90025-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Evidence is presented to suggest that N-acetyltyramine is the main intermediate on the pathway to N-acetyldopamine when S. gregaria thoracic ganglia are incubated with either [3H]-tyrosine or [3H]-tyramine. The subsequent o-hydroxylation of N-acetyltyramine is stimulated by ascorbic acid and inhibited by 5-fluorotryptamine. It appears to be catalyzed by an o-hydroxylase with cofactor and substrate specificities different from either mammalian tyrosine hydroxylase or tyrosinases from various sources [Calliphora and Periplaneta americana].

引用

页码：571 / 577

页数：7

共 19 条

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