A COMPARISON OF THE GROWTH-HORMONE RESPONSES TO CLONIDINE AND APOMORPHINE IN THE SAME PATIENTS WITH ENDOGENOUS-DEPRESSION

被引：45

作者：

CORN, TH

HALE, AS

THOMPSON, C

BRIDGES, PK

CHECKLEY, SA

机构：

[1] INST PSYCHIAT, DECRESPIGNY PK, DENMARK HILL, LONDON SE5 8AF, ENGLAND

[2] BROOK GEN HOSP, GEOFFREY KNIGHT PSYCHOSURG UNIT, LONDON SE18 41W, ENGLAND

[3] GUYS HOSP, SCH MED, LONDON SE1 9RT, ENGLAND

[4] MAUDSLEY HOSP, LONDON SE5 8AF, ENGLAND

来源：

BRITISH JOURNAL OF PSYCHIATRY | 1984年 / 144卷 / JUN期

关键词：

D O I：

10.1192/bjp.144.6.636

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

The growth hormone responses to clonidine (1.3 .mu.g/kg) and apomorphine (0.005 mg/kg) were measured in 8 drug free patients with endogenous depression. In these patients the growth hormone responses to clonidine were significantly smaller than to apomorphine. As these doses of clonidine and apomorphine have previously been reported to cause similar growth hormone responses in normal subjects, these findings support the hypothesis of a defect in the adrenergic but not the dopaminergic regulation of growth hormone in patients with endogenous depression.

引用

页码：636 / 639

页数：4

共 30 条

[1] THE DIAGNOSIS OF DEPRESSIVE SYNDROMES AND THE PREDICTION OF ECT RESPONSE [J].