Metabolism of citrulline in man

被引：101

作者：

Rabier, D

Kamoun, P

机构：

[1] Laboratoire Biochimie Médicale B-URA CNRS 1335, Université René Descartes Hôpital Necker -Enfants Malades, Paris Cedex 15, F-75743, 149, rue de Sèvres

来源：

AMINO ACIDS | 1995年 / 9卷 / 04期

关键词：

amino acids; citrulline;

D O I：

10.1007/BF00807268

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Citrulline is a non protein amino acid involved in three important metabolic pathways, the intrahepatic transformation of ammonia to urea, the de novo synthesis of arginine from glutamine in gut and kidney, the nitric oxide synthesis. The two first pathways use the same enzyme activities but are regulated in different way. This review describe these pathways and their regulation in different tissues. In the light of our knowledge we tried to explain the physiological and pathological (inherited or acquired) variations in man.

引用

页码：299 / 316

页数：18

共 92 条

[1]

AOYAGI K, 1979, BIOCHIM BIOPHYS ACTA, V587, P515

[2]

BOUBY N, 1993, KIDNEY INT, V49, P676

[3] EVIDENCE FOR THE EXISTENCE OF AN ORNITHINE-CITRULLINE ANTIPORTER IN RAT-LIVER MITOCHONDRIA [J].

BRADFORD, NM ;

MCGIVAN, JD .

FEBS LETTERS, 1980, 113 (02) :294-298

[4]

BREMER HJ, 1981, DISTURBANCES AMINO A, P203

[5] ORNITHINE TRANSCARBAMYLASE DEFICIENCIES IN HUMAN MALES KINETIC AND IMMUNOCHEMICAL CLASSIFICATION [J].

BRIAND, P ;

FRANCOIS, B ;

RABIER, D ;

CATHELINEAU, L .

BIOCHIMICA ET BIOPHYSICA ACTA, 1982, 704 (01) :100-106

[6]

BROSNAN JT, 1976, UREA CYCLE, P443

[7] EARLY ALTERATIONS OF PLASMA-FREE AMINO-ACIDS IN CHRONIC-RENAL-FAILURE [J].

CEBALLOS, I ;

CHAUVEAU, P ;

GUERIN, V ;

BARDET, J ;

PARVY, P ;

KAMOUN, P ;

JUNGERS, P .

CLINICA CHIMICA ACTA, 1990, 188 (02) :101-108

[8] CATALYTIC ACCELERATION OF UREA-DIACETYLMONOXIME-PHENAZONE REACTION AND ITS APPLICATION TO AUTOMATIC ANALYSIS [J].

CERIOTTI, G ;

SPANDRIO, L .

CLINICA CHIMICA ACTA, 1965, 11 (06) :519-&

[9]

Chappell JB, 1972, MOL BASIS BIOL TRANS, P55

[10] AMINO-ACID PROFILE IN PYRUVATE-CARBOXYLASE DEFICIENCY - COMPARISON WITH SOME OTHER METABOLIC DISORDERS [J].

CHARPENTIER, C ;

TETAU, JM ;

OGIER, H ;

SAUDUBRAY, JM ;

COUDE, FX ;

LEMONNIER, A .

JOURNAL OF INHERITED METABOLIC DISEASE, 1982, 5 :11-12

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