PULMONARY VASODILATORY EFFECTS OF 12 AND 60 PARTS-PER-MILLION INHALED NITRIC-OXIDE IN CHILDREN WITH VENTRICULAR SEPTAL-DEFECT

被引：28

作者：

DAY, RW ^{[1
]}

LYNCH, JM ^{[1
]}

SHADDY, RE ^{[1
]}

ORSMOND, GS ^{[1
]}

机构：

[1] UNIV UTAH,SALT LAKE CITY,UT 84113

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 1995年 / 75卷 / 02期

关键词：

D O I：

10.1016/S0002-9149(00)80080-6

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In conclusion, inhaled nitric oxide selectively decreased pulmonary vascular resistance of children with VSD and moderate pulmonary hypertension. During 7-minute intervals, pulmonary vascular resistance was selectively decreased to a similar extent by 12 and 60 ppm inhaled nitric oxide while breathing air or supplemental oxygen. Pulmonary vascular resistance was also decreased by supplemental oxygen alone; however, there was a concomitant increase in systemic vascular resistance. Pulmonary vascular resistance decreased to a greater extent with oxygen and inhaled nitric oxide than with either nitric oxide or oxygen alone. © 1995 Excerpta Medica, Inc. All rights reserved under the United States, International and Pan-American Copyright Conventions.

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页码：196 / 198

页数：3

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