2 PATTERNS OF FIRING IN HUMAN NEOCORTICAL NEURONS

被引：34

作者：

FOEHRING, RC ^{[1
]}

WYLER, AR ^{[1
]}

机构：

[1] UNIV TENNESSEE,CTR HLTH SCI,DEPT NEUROSURG,MEMPHIS,TN 38163

来源：

NEUROSCIENCE LETTERS | 1990年 / 110卷 / 03期

关键词：

Bursting; Epilepsy; Firing behavior; Human neocortex; Intracellular recording; Voltage dependence;

D O I：

10.1016/0304-3940(90)90860-C

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Intracellular recordings were made in slices of human neocortex removed for surgical treatment of epilepsy. In response to prolonged suprathreshold current injection, regular spiking neurons (67.5% of sample) responded by repetitive firing throughout the stimulus from all membrane potentials. Bursting neurons (32.5% of sample) responded with a burst of 2-3 spikes which rode upon a voltage-dependent slow depolarization. Bursting behavior was only observed from membrane potentials more negative than -65 mV. © 1990.

引用

页码：279 / 285

页数：7

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