INTERINDIVIDUAL VARIATIONS IN DRUG DISPOSITION - CLINICAL IMPLICATIONS AND METHODS OF INVESTIGATION

被引：137

作者：

BREIMER, DD

机构：

来源：

CLINICAL PHARMACOKINETICS | 1983年 / 8卷 / 05期

关键词：

D O I：

10.2165/00003088-198308050-00001

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：371 / 377

页数：7

共 34 条

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[2] INTRAINDIVIDUAL VARIATION IN DRUG DISPOSITION [J].

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PANTUCK, EJ ;

HSIAO, KC ;

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[3] FAMILY STUDY OF ANTIPYRINE CLEARANCE [J].

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[4] COMPARISON OF THE INVIVO AND INVITRO RATES OF FORMATION OF THE 3 MAIN OXIDATIVE METABOLITES OF ANTIPYRINE IN MAN [J].

BOOBIS, AR ;

BRODIE, MJ ;

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BLAIR, IA ;

MURRAY, S ;

DAVIES, DS .

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[5]

BREIMER DD, 1983, PHARMACOKINETICS MOD

[6]

BREIMER DD, 1980, BETTER SAFETY DRUGS

[7]

CONNEY AH, 1980, MICROSOMESDRUG OXIDA, P1103

[8] 3-HYDROXYMETHYL ANTIPYRINE EXCRETION IN URINE AFTER AN ORAL DOSE OF ANTIPYRINE - A RECONSIDERATION OF PREVIOUSLY PUBLISHED AND SYNTHESIS OF A PURE REFERENCE SUBSTANCE [J].

DANHOF, M ;

TEUNISSEN, MWE ;

BREIMER, DD .

PHARMACOLOGY, 1982, 24 (03) :181-184

[9] INFLUENCE OF THE GENETICALLY CONTROLLED DEFICIENCY IN DEBRISOQUINE HYDROXYLATION ON ANTIPYRINE METABOLITE FORMATION [J].

DANHOF, M ;

IDLE, JR ;

TEUNISSEN, MWE ;

SLOAN, TP ;

BREIMER, DD ;

SMITH, RL .

PHARMACOLOGY, 1981, 22 (06) :349-358

[10] ASSAY OF ANTIPYRINE AND ITS PRIMARY METABOLITES IN PLASMA, SALIVA AND URINE BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY AND SOME PRELIMINARY-RESULTS IN MAN [J].

DANHOF, M ;

GROOTVANDERVIS, ED ;

BREIMER, DD .

PHARMACOLOGY, 1979, 18 (04) :210-223

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