CASCADE CYCLIZATION - SYNTHESIS OF (+)-TUBERINE

被引：17

作者：

TABER, DF

BHAMIDIPATI, RS

THOMAS, ML

机构：

[1] Department of Chemistry and Biochemistry, University of Delaware, Newark

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1994年 / 59卷 / 12期

关键词：

D O I：

10.1021/jo00091a038

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Asymmetric dihydroxylation of epoxide 12 led, via biomimetic epoxide opening, to tetrahydrofuran 13. Acetylation of 13 then gave the antibiotic terpene (+)-tuberine (14). In the course of this work, the absolute configuration of (+)-tuberine was corrected.

引用

页码：3442 / 3444

页数：3

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