DIAMETER AND COMPLIANCE IN THE MALE HUMAN ABDOMINAL-AORTA - INFLUENCE OF AGE AND AORTIC-ANEURYSM

被引:148
作者
LANNE, T
SONESSON, B
BERGQVIST, D
BENGTSSON, H
GUSTAFSSON, D
机构
[1] Department of Surgery, Malmö General Hospital, Lund University, Malmö
[2] Department of Physiology, Lund University, Lund
来源
EUROPEAN JOURNAL OF VASCULAR SURGERY | 1992年 / 6卷 / 02期
关键词
ULTRASOUND; ULTRASONIC ECHO-TRACKING; AORTA; AORTIC DIAMETER; ARTERIAL BLOOD PRESSURE; COMPLIANCE; ELASTIC MODULUS; ATHEROSCLEROSIS; ANEURYSM;
D O I
10.1016/S0950-821X(05)80237-3
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
In this study changes in the diameter and compliance of the distal abdominal aorta (76 healthy Caucasian males, 5-71 years old) were determined non-invasively and related to age by means of an ultrasound phase-locked echo-tracking system. The diameter of the aorta increased not only in the period between 5 and 25 years of age, but also by about 30% between the ages of 25 and 71. The pressure diameter curves at 25, 51 and 70 years were non-linear with flattening between 90 and 110 mmHg, and the slope of the curves declined with age. Thus, the pressure strain elastic modulus (Ep) and stiffness (beta) increased (i.e. compliance decreased) in an exponential manner according to age. A group of 37 males with aneurysmal widening of the distal abdominal aorta had a significant increase in Ep when compared to an age-matched control group. Furthermore, the ranges for both Ep and beta were much larger in the aneurysm group than in the control group, indicating diversity in the pathogenesis of the disease. The non-invasive ultrasonic method of phase-locked echo-tracking is an appropriate method for studying compliance in major arteries under a variety of pathophysiological conditions.
引用
收藏
页码:178 / 184
页数:7
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