MODIFIED MAZE PROCEDURE FOR PATIENTS WITH ATRIAL-FIBRILLATION UNDERGOING SIMULTANEOUS OPEN-HEART-SURGERY

Persistent atrial fibrillation (AF) leaves patients symptomatic and at increased risk of thromboembolism even after otherwise successful cardiac surgery. Methods and Results To treat AF secondary to cardiac lesions requiring surgery, we combined a modified maze procedure in 101 patients simultaneously undergoing valvular procedures (87), repair of congenital anomalies (12), and other procedures (2), including 24 repeat operations. Duration of AF varied from 0.1 to 30 years (average+/-SD, 8.8+/-7.0 years); the f-wave voltage ranged from 0 to 0.45 mV (0.15+/-0.09 mV); and cardiothoracic ratio varied from 40% to 99% (63+/-9%). Aortic cross-clamp time varied from 75 to 229 minutes (138+/-31 minutes), with bypass time ranging from 119 to 326 minutes (217+/-42 minutes). There were two early deaths (2%), no late deaths, and one episode of transient neurological ischemic attack in follow-up ranging from 1.0 to 3.1 years, for a total of 190 patient-years. Postoperative rhythms were sinus in 83 patients (82%), junctional in 4 (4%), and persistent AF in 14 (14%), each of whom had mitral valve disease. Patients with other underlying pathology had complete recovery of atrial rhythm. A normal-sized A wave was detected in 88% for transtricuspid flow and in 73% for transmitral flow, suggesting concomitant recovery of atrial contraction. Among 36 patients without mechanical valves, 30 (83%) with atrial rhythm and contraction have been taken off anticoagulation therapy, including 10 who are free of all medication. Conclusions. The results suggest that the combined approach is safe, effective, and indicated in patients who are judged capable of tolerating the procedure and likely to regain atrial rhythm.