MPTP TOXICITY - IMPLICATIONS FOR RESEARCH IN PARKINSONS-DISEASE

[1] ROLE OF N-METHYLTRANSFERASES IN THE NEUROTOXICITY ASSOCIATED WITH THE METABOLITES OF 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE (MPTP) AND OTHER 4-SUBSTITUTED PYRIDINES PRESENT IN THE ENVIRONMENT [J]. BIOCHEMICAL PHARMACOLOGY, 1986, 35 (19) : 3359 - 3363

[2] ANTIOXIDANTS FAIL TO INHIBIT DEPLETION OF STRIATAL DOPAMINE BY MPTP [J]. NEUROLOGY, 1986, 36 (05) : 735 - 735

[3] COMPARATIVE BEHAVIORAL, BIOCHEMICAL AND PIGMENTARY EFFECTS OF MPTP, MPP+ AND PARAQUAT IN RANA-PIPIENS [J]. LIFE SCIENCES, 1985, 37 (16) : 1529 - 1538

[4] NEW AMPHIBIAN MODELS FOR THE STUDY OF 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE (MPTP) [J]. LIFE SCIENCES, 1985, 36 (11) : 1125 - 1134

[5] INCREASED LIFE EXPECTANCY RESULTING FROM ADDITION OF L-DEPRENYL TO MADOPAR TREATMENT IN PARKINSONS-DISEASE - A LONGTERM STUDY [J]. JOURNAL OF NEURAL TRANSMISSION, 1985, 64 (02) : 113 - 127

[6] BIRKMAYER W, 1961, Wien Klin Wochenschr, V73, P787

[7] REPEATED ADMINISTRATION OF N-METHYL-4-PHENYL-1,2,5,6-TETRAHYDROPYRIDINE TO RATS IS NOT TOXIC TO STRIATAL DOPAMINE NEURONS [J]. BIOCHEMICAL PHARMACOLOGY, 1984, 33 (11) : 1747 - 1752

[8] A PRIMATE MODEL OF PARKINSONISM - SELECTIVE DESTRUCTION OF DOPAMINERGIC-NEURONS IN THE PARS COMPACTA OF THE SUBSTANTIA NIGRA BY N-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (14): : 4546 - 4550

[9] BURNS RS, 1984, CAN J NEUROL SCI, V11, P166

[10] THE CLINICAL SYNDROME OF STRIATAL DOPAMINE DEFICIENCY - PARKINSONISM INDUCED BY 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE (MPTP) [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1985, 312 (22) : 1418 - 1421

[1] ROLE OF N-METHYLTRANSFERASES IN THE NEUROTOXICITY ASSOCIATED WITH THE METABOLITES OF 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE (MPTP) AND OTHER 4-SUBSTITUTED PYRIDINES PRESENT IN THE ENVIRONMENT [J]. BIOCHEMICAL PHARMACOLOGY, 1986, 35 (19) : 3359 - 3363

[2] ANTIOXIDANTS FAIL TO INHIBIT DEPLETION OF STRIATAL DOPAMINE BY MPTP [J]. NEUROLOGY, 1986, 36 (05) : 735 - 735

[3] COMPARATIVE BEHAVIORAL, BIOCHEMICAL AND PIGMENTARY EFFECTS OF MPTP, MPP+ AND PARAQUAT IN RANA-PIPIENS [J]. LIFE SCIENCES, 1985, 37 (16) : 1529 - 1538

[4] NEW AMPHIBIAN MODELS FOR THE STUDY OF 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE (MPTP) [J]. LIFE SCIENCES, 1985, 36 (11) : 1125 - 1134

[5] INCREASED LIFE EXPECTANCY RESULTING FROM ADDITION OF L-DEPRENYL TO MADOPAR TREATMENT IN PARKINSONS-DISEASE - A LONGTERM STUDY [J]. JOURNAL OF NEURAL TRANSMISSION, 1985, 64 (02) : 113 - 127

[6] BIRKMAYER W, 1961, Wien Klin Wochenschr, V73, P787

[7] REPEATED ADMINISTRATION OF N-METHYL-4-PHENYL-1,2,5,6-TETRAHYDROPYRIDINE TO RATS IS NOT TOXIC TO STRIATAL DOPAMINE NEURONS [J]. BIOCHEMICAL PHARMACOLOGY, 1984, 33 (11) : 1747 - 1752

[8] A PRIMATE MODEL OF PARKINSONISM - SELECTIVE DESTRUCTION OF DOPAMINERGIC-NEURONS IN THE PARS COMPACTA OF THE SUBSTANTIA NIGRA BY N-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (14): : 4546 - 4550

[9] BURNS RS, 1984, CAN J NEUROL SCI, V11, P166

[10] THE CLINICAL SYNDROME OF STRIATAL DOPAMINE DEFICIENCY - PARKINSONISM INDUCED BY 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE (MPTP) [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1985, 312 (22) : 1418 - 1421