INOSITOL STIMULATES DNA AND PROTEIN-SYNTHESIS, AND EXPANSION BY RABBIT BLASTOCYSTS INVITRO

被引：22

作者：

FAHY, MM ^{[1
]}

KANE, MT ^{[1
]}

机构：

[1] NATL UNIV IRELAND UNIV COLL GALWAY,DEPT PHYSIOL,GALWAY,IRELAND

来源：

HUMAN REPRODUCTION | 1992年 / 7卷 / 04期

关键词：

RABBIT; INOSITOL; BLASTOCYST; DNA; PROTEIN;

D O I：

10.1093/oxfordjournals.humrep.a137688

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The effect of different concentrations (0, 0.6, 3, 15, 75 and 375-mu-M) of myo-inositol on the development of rabbit morulae to expanded blastocysts was investigated in terms of blastocyst expansion and synthesis of DNA and protein, as measured by incorporation of [H-3]thymidine and [C-14]amino acids into acid-precipitable material. A concentration of 15-mu-M inositol caused a 2.8-fold increase in blastocyst expansion (P < 0.01), a 9.9-fold increase in thymidine incorporation into DNA (P < 0.01) and a 3.6-fold increase in amino acid incorporation into protein (P < 0.01). There were no significant differences in the range from 15 to 375-mu-M inositol.

引用

页码：550 / 552

页数：3

共 17 条

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