The results of low-temperature photoluminescence (PL) measurements on wurtzite GaN with applied pressure up to over 50 kbar were reported. The samples were single-crystal GaN epilayer films grown by metalorganic chemical vapor deposition (MOCVD) on sapphire substrates. The PL spectra of the MOCVD GaN samples were governed by strong, narrow, near band-edge emission structures corresponding to radiative decay of bound and free excitons and a broad emission band in the yellow band with the maxima around 2.25 eV. The pressure coefficients for the observed excitonic emission lines were determined to be 3.9 meV/kbar, which yielded a direct measure of the pressure coefficient of wurtzite GaN direct Γ band gap. The experimental value of the hydrostatic deformation potential of the band gap was also obtained from the results.