INTEGRATION OF PLASMID P-PHI-HL INTO PHAGE GENOMES DURING INFECTION OF HALOBACTERIUM-HALOBIUM R1-L WITH PHAGE PHI-HL1

被引：4

作者：

SCHNABEL, H

机构：

来源：

MOLECULAR AND GENERAL GENETICS | 1984年 / 197卷 / 01期

关键词：

D O I：

10.1007/BF00327917

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The plasmid p.PHI.HL, which arose by circularization of the invertible L segment of phage .PHI.H, integrates into phage DNA during growth of phage .PHI.HL1 on the H. halobium strain R1-L. More than 1% of all phage DNA isolated from such a lysate contains integrated p.PHI.HL. Recombination between the plasmid and the homologous L segment in the phage genome occurs with equally high frequency on both sides of a 1 kilobase insertion present in .PHI.HL1 DNA but absent from p.PHI.HL. Homologous recombination is an important factor in the generation of DNA rearrangements in H. halobium.

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页码：19 / 23

页数：5

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