SPINAL-CORD INFARCTS DURING LONG-TERM INHIBITION OF NITRIC-OXIDE SYNTHASE IN RATS

被引：63

作者：

BLOT, S

ARNAL, JF

XU, Y

GRAY, F

MICHEL, JB

机构：

[1] INSERM, U367, F-75005 PARIS, FRANCE

[2] ECOLE VET ALFORT, MAISONS ALFORT, FRANCE

[3] INSERM, U153, PARIS, FRANCE

[4] HOP RAY POINCARE, GARCHES, FRANCE

来源：

STROKE | 1994年 / 25卷 / 08期

关键词：

HYPERTENSION; NITRIC OXIDE; SPINAL CORD; RATS;

D O I：

10.1161/01.STR.25.8.1666

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Background and Purpose Chronic hypertension is a major predisposing factor for stroke in humans. It has recently been shown that long-term inhibition of nitric oxide synthase activity causes a gradual time-dependent increase in arterial blood pressure in rats. We used this new animal model of chronic hypertension to study the occurrence and spatial features of infarcts in the central nervous system.

引用

页码：1666 / 1673

页数：8

共 54 条

[1] DETERMINANTS OF AORTIC CYCLIC GUANOSINE-MONOPHOSPHATE IN HYPERTENSION INDUCED BY CHRONIC INHIBITION OF NITRIC-OXIDE SYNTHASE
ARNAL, JF
WARIN, L
MICHEL, JB
[J]. JOURNAL OF CLINICAL INVESTIGATION, 1992, 90 (02) : 647 - 652
[2] NITRIC-OXIDE ACTIVATES GUANYLATE CYCLASE AND INCREASES GUANOSINE 3'-5'-CYCLIC MONOPHOSPHATE LEVELS IN VARIOUS TISSUE PREPARATIONS
ARNOLD, WP
MITTAL, CK
KATSUKI, S
MURAD, F
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1977, 74 (08) : 3203 - 3207
[3] CHRONIC BLOCKADE OF NITRIC-OXIDE SYNTHESIS IN THE RAT PRODUCES SYSTEMIC HYPERTENSION AND GLOMERULAR DAMAGE
BAYLIS, C
MITRUKA, B
DENG, A
[J]. JOURNAL OF CLINICAL INVESTIGATION, 1992, 90 (01) : 278 - 281
[4] LOCALIZATION OF NITRIC-OXIDE SYNTHASE INDICATING A NEURAL ROLE FOR NITRIC-OXIDE
BREDT, DS
HWANG, PM
SNYDER, SH
[J]. NATURE, 1990, 347 (6295) : 768 - 770
[5] NITRIC-OXIDE SYNTHASE PROTEIN AND MESSENGER-RNA ARE DISCRETELY LOCALIZED IN NEURONAL POPULATIONS OF THE MAMMALIAN CNS TOGETHER WITH NADPH DIAPHORASE
BREDT, DS
GLATT, CE
HWANG, PM
FOTUHI, M
DAWSON, TM
SNYDER, SH
[J]. NEURON, 1991, 7 (04) : 615 - 624
[6] CLONED AND EXPRESSED NITRIC-OXIDE SYNTHASE STRUCTURALLY RESEMBLES CYTOCHROME-P-450 REDUCTASE
BREDT, DS
HWANG, PM
GLATT, CE
LOWENSTEIN, C
REED, RR
SNYDER, SH
[J]. NATURE, 1991, 351 (6329) : 714 - 718
[7] N(G)-NITRO L-ARGININE METHYL-ESTER AND OTHER ALKYL ESTERS OF ARGININE ARE MUSCARINIC RECEPTOR ANTAGONISTS
BUXTON, ILO
CHEEK, DJ
ECKMAN, D
WESTFALL, DP
SANDERS, KM
KEEF, KD
[J]. CIRCULATION RESEARCH, 1993, 72 (02) : 387 - 395
[8] IMMUNOENZYMATIC LABELING OF MONOCLONAL-ANTIBODIES USING IMMUNE-COMPLEXES OF ALKALINE-PHOSPHATASE AND MONOCLONAL ANTI-ALKALINE PHOSPHATASE (APAAP COMPLEXES)
CORDELL, JL
FALINI, B
ERBER, WN
GHOSH, AK
ABDULAZIZ, Z
MACDONALD, S
PULFORD, KAF
STEIN, H
MASON, DY
[J]. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, 1984, 32 (02) : 219 - 229
[9] A NOVEL NEURONAL MESSENGER MOLECULE IN BRAIN - THE FREE-RADICAL, NITRIC-OXIDE
DAWSON, TM
DAWSON, VL
SNYDER, SH
[J]. ANNALS OF NEUROLOGY, 1992, 32 (03) : 297 - 311
[10] DIJKSTRA CD, 1985, IMMUNOLOGY, V54, P589

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