THE INVITRO UNSCHEDULED DNA-SYNTHESIS (UDS) ASSAY IN RAT PRIMARY HEPATOCYTES - EVALUATION OF 24 DRUG CANDIDATES

被引：11

作者：

AARON, CS ^{[1
]}

HARBACH, PR ^{[1
]}

STEINMETZ, KL ^{[1
]}

BAKKE, JP ^{[1
]}

MIRSALIS, JC ^{[1
]}

机构：

[1] SRI INT,CELLULAR & GENET TOXICOL,MENLO PK,CA 94025

来源：

MUTATION RESEARCH | 1989年 / 223卷 / 02期

关键词：

D O I：

10.1016/0165-1218(89)90042-6

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

引用

页码：141 / 151

页数：11

共 16 条

[1] COMPARATIVE MUTAGENICITY TESTING OF A DRUG CANDIDATE, U-48753E - MECHANISM OF INDUCTION OF GENE-MUTATIONS IN MAMMALIAN-CELLS AND QUANTITATION OF POTENTIAL HAZARD
AARON, CS
STANKOWSKI, LF
HARBACH, PR
VALENCIA, R
MAYO, JK
MIRSALIS, J
MAZUREK, JH
STEINMETZ, KL
WISER, SK
ZIMMER, DM
TRZOS, RJ
[J]. MUTATION RESEARCH, 1989, 223 (02): : 111 - 120
[2] COMPARISON OF THE AS52/XPRT AND THE CHO/HPRT ASSAYS - EVALUATION OF 6 DRUG CANDIDATES
AARON, CS
STANKOWSKI, LF
[J]. MUTATION RESEARCH, 1989, 223 (02): : 121 - 128
[3] THE INVITRO UNSCHEDULED DNA-SYNTHESIS (UDS) ASSAY IN RAT PRIMARY HEPATOCYTES - EVALUATION OF 2-FUROIC ACID AND 7 DRUG CANDIDATES
AARON, CS
HARBACH, PR
WISER, SK
GRZEGORCZYK, CR
SMITH, AL
[J]. MUTATION RESEARCH, 1989, 223 (02): : 163 - 169
[4] THE CHO/HPRT ASSAY - EVALUATION OF 19 DRUG CANDIDATES
AARON, CS
STANKOWSKI, LF
ZIMMER, DM
[J]. MUTATION RESEARCH, 1989, 223 (02): : 153 - 161
[5] THE MOUSE BONE-MARROW MICRONUCLEUS TEST - EVALUATION OF 21 DRUG CANDIDATES
AARON, CS
SORG, R
ZIMMER, D
[J]. MUTATION RESEARCH, 1989, 223 (02): : 129 - 140
[6] THE SALMONELLA MUTAGENICITY TEST - EVALUATION OF 29 DRUG CANDIDATES
AARON, CS
MAZUREK, J
ZIMMER, DM
SWENSON, DH
[J]. MUTATION RESEARCH, 1989, 223 (02): : 171 - 182
[7] Brusick D., 1980, SPRINGER NEW YORK NY, DOI [10.1007/978-1-4615-7661-7, DOI 10.1007/978-1-4615-7661-7]
[8] A PROTOCOL AND GUIDE FOR THE INVITRO RAT HEPATOCYTE DNA-REPAIR ASSAY
BUTTERWORTH, BE
ASHBY, J
BERMUDEZ, E
CASCIANO, D
MIRSALIS, J
PROBST, G
WILLIAMS, G
[J]. MUTATION RESEARCH, 1987, 189 (02): : 113 - 121
[9] Friedberg E. C., 1985, DNA REPAIR
[10] HARBACH PR, 1986, ENVIRON MOL MUTAGEN, V8, P34

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