A SELECTIVE SCREEN FOR TRANSPOSABLE ELEMENT MOBILIZATION IN DROSOPHILA-MELANOGASTER

被引：5

作者：

CLARK, SH

CHOVNICK, A

机构：

来源：

ENVIRONMENTAL MUTAGENESIS | 1985年 / 7卷 / 04期

关键词：

D O I：

10.1002/em.2860070405

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

A selective system is described that provides a simple and sensitive assay for the detection and analysis of induced mobile element transpositions in D. melanogaster. The system will detect a single event in samples > 106 and thus provides a eukaryotic assay system for monitoring the induction of transposition by a variety of agents including, but not limited to, chemical carcinogens and toxins, ionizing radiation and various environmental pollutants. The experimental system focuses on an X-linked rosy+ transposon and a conditional lethal system that permits the detection of a single transposition event in very large samples. The results of a pilot experiment utilizing this system are presented.

引用

页码：439 / 449

页数：11

共 34 条

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