FORMATION OF (R)-CONFIGURATED TETRAHYDROPROTOBERBERINE ALKALOIDS INVIVO AND INVITRO

被引：6

作者：

BAUER, W ^{[1
]}

ZENK, MH ^{[1
]}

机构：

[1] UNIV MUNICH,LEHRSTUHL PHARMAZEUT BIOL,KARLSTR 29,W-8000 MUNICH 2,GERMANY

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 04期

关键词：

D O I：

10.1016/S0040-4039(00)79475-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A highly stereoselective and reversible enzyme system, using NADPH and protoberberine alkaloids, was discovered in Corydalis cava bulbs catalyzing the formation of (R)-configurated tetrahydroprotoberberine alkaloids; the hitherto assumed precursor role of (R)-reticuline for these alkaloids is incorrect.

引用

页码：487 / 490

页数：4

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