DIGITAL-SIMULATION OF MEMBRANE VOLTAGES AND CURRENTS IN NERVE AND MUSCLE-FIBERS

被引：2

作者：

OWEN, EW

WARING, W

SHOJI, FF

PRAKASH, CV

机构：

[1] UNIV CALIF DAVIS, DEPT PHYS MED & REHABIL, DAVIS, CA 96515 USA

[2] UNIV CALIF DAVIS, DEPT ELECT ENGN, DAVIS, CA 96515 USA

[3] COLLINS RADIO CO, CEDAR RAPIDS, IA 52406 USA

来源：

COMPUTER PROGRAMS IN BIOMEDICINE | 1976年 / 6卷 / 02期

关键词：

D O I：

10.1016/0010-468X(76)90027-1

中图分类号：

TP39 [计算机的应用];

学科分类号：

081203 ; 0835 ;

摘要：

Digital computer simulations of membrane voltages and currents in axons and muscle fibers are described. The simulations which allow calculations on a nonuniform fiber, are based on the discrete Hodgkin-Huxley and Falk-Fatt equations. An efficient algorithm is used to solve the set of equations generated. Voltage and current at the natural end of a muscle fiber are calculated and compared with measurements by other investigators.

引用

页码：63 / 73

页数：11

共 10 条

[1] SLOW CHANGES IN POTASSIUM PERMEABILITY IN SKELETAL MUSCLE [J].

ADRIAN, RH ;

CHANDLER, WK ;

HODGKIN, AL .

JOURNAL OF PHYSIOLOGY-LONDON, 1970, 208 (03) :645-+

[2] DIFITAL COMPUTER SOLUTIONS FOR EXCITATION AND PROPAGATION OF NERVE IMPULSE [J].

COOLEY, JW ;

DODGE, FA .

BIOPHYSICAL JOURNAL, 1966, 6 (05) :583-&

[3] LINEAR ELECTRICAL PROPERTIES OF STRIATED MUSCLE FIBRES OBSERVED WITH INTRACELLULAR ELECTRODES [J].

FALK, G ;

FATT, P .

PROCEEDINGS OF THE ROYAL SOCIETY SERIES B-BIOLOGICAL SCIENCES, 1964, 160 (978) :69-+

[4]

FIELD J, 1959, HDB PHYSIOLOGY 1, V1

[5]

GERALD CF, 1970, APPLIED NUMERICAL AN

[6] A QUANTITATIVE DESCRIPTION OF MEMBRANE CURRENT AND ITS APPLICATION TO CONDUCTION AND EXCITATION IN NERVE [J].

HODGKIN, AL ;

HUXLEY, AF .

JOURNAL OF PHYSIOLOGY-LONDON, 1952, 117 (04) :500-544

[7] PROPGATION OF ELECTRIC ACTIVITY IN MOTOR NERVE TERMINALS [J].

KATZ, B ;

MILEDI, R .

PROCEEDINGS OF THE ROYAL SOCIETY SERIES B-BIOLOGICAL SCIENCES, 1965, 161 (985) :453-+

[8] THRESHOLD CONDITIONS FOR INITIATION OF ACTION POTENTIALS BY EXCITABLE CELLS [J].

NOBLE, D ;

STEIN, RB .

JOURNAL OF PHYSIOLOGY-LONDON, 1966, 187 (01) :129-&

[9]

PRAKASH CV, 1972, THESIS U CALIFORNIA

[10]

TAYLOR RE, 1963, PHYSICAL TECHNIQUE B, V6

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