SOMATIC MUTATION ALTERS AFFINITY AND SPECIFICITY

被引：2

作者：

DIAMOND, B

CHIEN, N

SCHARFF, M

机构：

[1] YESHIVA UNIV ALBERT EINSTEIN COLL MED,DEPT MICROBIOL & IMMUNOL,BRONX,NY 10461

[2] YESHIVA UNIV ALBERT EINSTEIN COLL MED,DEPT MED & CELL BIOL,BRONX,NY 10461

[3] YESHIVA UNIV ALBERT EINSTEIN COLL MED,IRVINGTON HOUSE INST,BRONX,NY 10461

来源：

ANNALES DE L INSTITUT PASTEUR-IMMUNOLOGY | 1985年 / C136卷 / 02期

关键词：

D O I：

10.1016/S0769-2625(85)80057-X

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

引用

页码：267 / 271

页数：5

共 19 条

[1] ANTI-PHOSPHORYLCHOLINE ANTIBODIES OF THE T15 IDIOTYPE ARE OPTIMALLY PROTECTIVE AGAINST STREPTOCOCCUS-PNEUMONIAE [J].

BRILES, DE ;

FORMAN, C ;

HUDAK, S ;

CLAFLIN, JL .

JOURNAL OF EXPERIMENTAL MEDICINE, 1982, 156 (04) :1177-1185

[2] ANTIGEN-BINDING MUTANTS OF MOUSE MYELOMA CELLS [J].

COOK, WD ;

SCHARFF, MD .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1977, 74 (12) :5687-5691

[3] SOMATIC MUTATION IN A CULTURED MOUSE MYELOMA CELL AFFECTS ANTIGEN-BINDING [J].

COOK, WD ;

RUDIKOFF, S ;

GIUSTI, AM ;

SCHARFF, MD .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1982, 79 (04) :1240-1244

[4] A SINGLE VH GENE SEGMENT ENCODES THE IMMUNE-RESPONSE TO PHOSPHORYLCHOLINE - SOMATIC MUTATION IS CORRELATED WITH THE CLASS OF THE ANTIBODY [J].

CREWS, S ;

GRIFFIN, J ;

HUANG, H ;

CALAME, K ;

HOOD, L .

CELL, 1981, 25 (01) :59-66

[5] STRUCTURAL BASIS OF ANTIBODY FUNCTION [J].

DAVIES, DR ;

METZGER, H .

ANNUAL REVIEW OF IMMUNOLOGY, 1983, 1 :87-117

[6]

DIAMOND B, P NAT ACAD SCI WASH

[7]

EILAT D, 1984, J IMMUNOL, V133, P489

[8]

GEARHART P, 1981, NATURE LOND, V291, P28

[9]

GUISTI AM, 1984, THESIS A EINSTEIN CO

[10] ATTEMPTS TO LOCATE RESIDUES IN COMPLEMENTARITY-DETERMINING REGIONS OF ANTIBODY COMBINING SITES THAT MAKE CONTACT WITH ANTIGEN [J].

KABAT, EA ;

WU, TT ;

BILOFSKY, H .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1976, 73 (02) :617-619

← 1 2 →