THE USE OF QUESTIONNAIRE DATA TO CLASSIFY PERIMENOPAUSAL AND PREMENOPAUSAL STATUS

被引:13
作者
COOPER, GS
BAIRD, DD
机构
[1] Department of Epidemiology, University of North Carolina, Chapel Hill, NC
[2] Epidemiology Branch, National Institute of Environmental Health Sciences, NC, Research Triangle Park
关键词
MENOPAUSAL STATUS; QUESTIONNAIRE ASSESSMENT; METHODOLOGY;
D O I
10.1097/00001648-199511000-00011
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 [公共卫生与预防医学]; 120402 [社会医学与卫生事业管理];
摘要
We assessed how well questionnaire data could classify peri- vs premenopausal status in 280 women, ages 38-49 years. Sixty-seven per cent of those who reported use of hormone replacement therapy begun when menstrual periods were irregular, or who had hot flashes at least once a day, or whose last menstrual period was at least 60 days in length, were perimenopausal by hormonal assay (early follicular phase serum follicle-stimulating hormone greater than or equal to 15 international units per liter), with a sensitivity of 0.56 [95% confidence interval (CI) = 0.41-0.72] and a specificity of 0.95 (95% CI = 0.93-0.98). In the classification of premenopausal status, the criterion of no menstrual cycle length changes in the past 5 years yielded the highest sensitivity (0.61; 95% CI = 0.54-0.67) and specificity (0.81; 95% CI = 0.68-0.93). With these few items, researchers can improve the classification of peri- and premenopausal status when longitudinal or hormonal assessments cannot be obtained.
引用
收藏
页码:625 / 628
页数:4
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