RAPID GENOTYPING OF LOW-DENSITY-LIPOPROTEIN RECEPTOR KNOCKOUT MICE USING A POLYMERASE CHAIN-REACTION TECHNIQUE

被引:24
作者
GAW, A
MANCINI, FP
ISHIBASHI, S
机构
[1] UNIV TEXAS,SW MED CTR,DEPT MOLEC GENET,DALLAS,TX 75235
[2] UNIV TOKYO,FAC MED,DEPT INTERNAL MED 3,TOKYO 113,JAPAN
关键词
MICE; LDL RECEPTOR; PCR; GENOTYPING;
D O I
10.1258/002367795780739944
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
A new method for the rapid genotyping of low density lipoprotein receptor knockout mice is described. This method using a polymerase chain reaction (PCR) technique may be performed on small tissue biopsies, and represents a significant advantage in time over conventional genotyping by Southern blot analyses.
引用
收藏
页码:447 / 449
页数:3
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