INHIBITION OF DIHYDROFOLATE-REDUCTASE FROM BACTERIAL AND VERTEBRATE SOURCES BY FOLATE, AMINOPTERIN, METHOTREXATE AND THEIR 5-DEAZA ANALOGS

被引：40

作者：

STONE, SR

MONTGOMERY, JA

MORRISON, JF

机构：

[1] AUSTRALIAN NATL UNIV,JOHN CURTIN SCH MED RES,DEPT BIOCHEM,CANBERRA,ACT 2601,AUSTRALIA

[2] SO RES INST,KETTERING MEYER LAB,BIRMINGHAM,AL 35255

来源：

BIOCHEMICAL PHARMACOLOGY | 1984年 / 33卷 / 02期

关键词：

D O I：

10.1016/0006-2952(84)90472-6

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：175 / 179

页数：5

共 21 条

[1] CRYSTALLINE DIHYDROPTEROYLGLUTAMIC ACID [J].

BLAKLEY, RL .

NATURE, 1960, 188 (4746) :231-232

[2]

BOLIN JT, 1982, J BIOL CHEM, V257, P13650

[3] TIGHT-BINDING INHIBITORS .1. KINETIC-BEHAVIOR [J].

CHA, S .

BIOCHEMICAL PHARMACOLOGY, 1975, 24 (23) :2177-2185

[4] TIGHT-BINDING INHIBITORS .2. NON-STEADY STATE NATURE OF INHIBITION OF MILK XANTHINE-OXIDASE BY ALLOPURINOL AND ALLOXANTHINE AND OF HUMAN ERYTHROCYTIC ADENOSINE DEAMINASE BY COFORMYCIN [J].

CHA, S ;

AGARWAL, RP ;

PARKS, RE .

BIOCHEMICAL PHARMACOLOGY, 1975, 24 (23) :2187-2197

[5] STEREOCHEMISTRY OF REDUCTION OF FOLIC-ACID USING DIHYDROFOLATE-REDUCTASE [J].

CHARLTON, PA ;

YOUNG, DW ;

BIRDSALL, B ;

FEENEY, J ;

ROBERTS, GCK .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1979, (20) :922-924

[6] C-13 NUCLEAR MAGNETIC-RESONANCE STUDY OF PROTONATION OF METHOTREXATE AND AMINOPTERIN BOUND TO DIHYDROFOLATE-REDUCTASE [J].

COCCO, L ;

GROFF, JP ;

TEMPLE, C ;

MONTGOMERY, JA ;

LONDON, RE ;

MATWIYOFF, NA ;

BLAKLEY, RL .

BIOCHEMISTRY, 1981, 20 (14) :3972-3978

[7] FITTING OF ENZYME KINETIC DATA WITHOUT PRIOR KNOWLEDGE OF WEIGHTS [J].

CORNISHBOWDEN, A ;

ENDRENYI, L .

BIOCHEMICAL JOURNAL, 1981, 193 (03) :1005-1008

[8]

Dawson R.M.C., 1969, DATA BIOCH RES

[9] ABSOLUTE-CONFIGURATION OF BIOLOGICAL TETRAHYDROFOLATES - CRYSTALLOGRAPHIC DETERMINATION [J].

FONTECILLACAMPS, JC ;

BUGG, CE ;

TEMPLE, C ;

ROSE, JD ;

MONTGOMERY, JA ;

KISLIUK, RL .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1979, 101 (20) :6114-6115

[10]

Gready J E, 1980, Adv Pharmacol Chemother, V17, P37, DOI 10.1016/S1054-3589(08)60007-1

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