A NOVEL CHICKEN HOMEOBOX-CONTAINING GENE EXPRESSED IN NEURULATING EMBRYOS

被引：12

作者：

SERRANO, J

SCAVO, L

ROTH, J

DELAROSA, EJ

DEPABLO, F

机构：

[1] CSIC, CTR INVEST BIOL, VELAZQUEZ 144, E-28006 MADRID, SPAIN

[2] E CAROLINA UNIV, SCH MED, GREENVILLE, NC 27858 USA

[3] UCSF SAN FRANCISCO, SAN FRANCISCO, CA 94143 USA

[4] JOHNS HOPKINS UNIV, SCH MED, BALTIMORE, MD 21224 USA

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1993年 / 190卷 / 01期

关键词：

D O I：

10.1006/bbrc.1993.1041

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We have isolated a cDNA clone from chicken embryo that contains a homeobox sequence (CHox-cad2). Analysis at the nucleotide and amino acid levels revealed closest similarity to the Xenopus Xcad1 and to other homeoboxes related to Drosophila caudal. RNA blot analysis showed hybridization of CHox-cad2 to two transcripts of 2.6 and 1.5 kb, present at day 1 of embryogenesis (E1). Using the highly sensitive polymerase chain reaction (PCR) to amplify cDNAs from embryonic RNAs from E0 (unincubated blastoderm) to E4, we confirmed the restricted expression of this homeobox sequence to the period of neurulation (E1). © 1993 Academic Press. Inc.

引用

页码：270 / 276

页数：7

共 16 条

[1]

ALTABA AR, 1989, NATURE, V341, P33

[2] ORGANIZER-SPECIFIC HOMEOBOX GENES IN XENOPUS-LAEVIS EMBRYOS [J].