学术探索
学术期刊
新闻热点
数据分析
智能评审

NEUROPEPTIDE-Y - AN OVERVIEW

被引：45
作者：
LEHMANN, J
机构：
[1] Neurology Division, Fondax Actam & Cie, Groupe de Recherche Servier, Puteaux
来源：
DRUG DEVELOPMENT RESEARCH | 1990年 / 19卷 / 04期
关键词：
behavior; blood pressure; endocrinology; food consumption; immunology; noradrenaline; NPY;
D O I：
10.1002/ddr.430190402
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Neuropeptide Y (NPY) has a broad distribution and numerous physiological functions in the peripheral and central nervous systems. The gene transcription and fundamentals of peptide processing have been elucidated. NPY levels and release are exquisitely sensitive to pharmacological and physiological manipulation. NPY receptors have been partially characterized pharmacologically. The effects of NPY on target organs and their implications for drugs interacting with the NPY system are described. Copyright © 1990 Wiley‐Liss, Inc.
引用
收藏
页码：329 / 351
页数：23
相关论文
共 162 条
  • [1] NEUROPEPTIDE-Y - VASOCONSTRICTOR EFFECTS AND POSSIBLE ROLE IN CEREBRAL VASOSPASM AFTER EXPERIMENTAL SUBARACHNOID HEMORRHAGE
    ABEL, PW
    HAN, C
    NOE, BD
    MCDONALD, JK
    [J]. BRAIN RESEARCH, 1988, 463 (02) : 250 - 258
  • [2] NEUROPEPTIDE-Y DIRECTLY INHIBITS GROWTH-HORMONE SECRETION BY HUMAN PITUITARY SOMATOTROPIC TUMORS
    ADAMS, EF
    VENETIKOU, MS
    WOODS, CA
    LACOUMENTA, S
    BURRIN, JM
    [J]. ACTA ENDOCRINOLOGICA, 1987, 115 (01): : 149 - 154
  • [3] DISTRIBUTION AND POSTPRANDIAL RELEASE OF PORCINE PEPTIDE-YY
    ADRIAN, TE
    BACARESEHAMILTON, AJ
    SMITH, HA
    CHOHAN, P
    MANOLAS, KJ
    BLOOM, SR
    [J]. JOURNAL OF ENDOCRINOLOGY, 1987, 113 (01) : 11 - 14
  • [4] NEUROPEPTIDE-Y DISTRIBUTION IN HUMAN-BRAIN
    ADRIAN, TE
    ALLEN, JM
    BLOOM, SR
    GHATEI, MA
    ROSSOR, MN
    ROBERTS, GW
    CROW, TJ
    TATEMOTO, K
    POLAK, JM
    [J]. NATURE, 1983, 306 (5943) : 584 - 586
  • [5] NEUROPEPTIDE-Y AND PANCREATIC-POLYPEPTIDE - EFFECTS ON THYROID-HORMONE SECRETION IN THE MOUSE
    AHREN, B
    [J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 1986, 126 (1-2) : 97 - 102
  • [6] MOLECULAR-STRUCTURE OF MAMMALIAN NEUROPEPTIDE-Y - ANALYSIS BY MOLECULAR-CLONING AND COMPUTER-AIDED COMPARISON WITH CRYSTAL-STRUCTURE OF AVIAN HOMOLOG
    ALLEN, J
    NOVOTNY, J
    MARTIN, J
    HEINRICH, G
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (08) : 2532 - 2536
  • [7] PRESENCE, DISTRIBUTION, AND PHARMACOLOGICAL EFFECTS OF NEUROPEPTIDE-Y IN MAMMALIAN GASTROINTESTINAL-TRACT
    ALLEN, JM
    HUGHES, J
    BLOOM, SR
    [J]. DIGESTIVE DISEASES AND SCIENCES, 1987, 32 (05) : 506 - 512
  • [8] NEUROPEPTIDE-Y IN THE GUINEA-PIG BILIARY-TRACT
    ALLEN, JM
    GU, J
    ADRIAN, TE
    POLAK, JM
    BLOOM, SR
    [J]. EXPERIENTIA, 1984, 40 (07): : 765 - 767
  • [9] INTERACTIONS BETWEEN NEUROPEPTIDE-Y AND ADRENERGIC SYSTEMS IN THE STIMULATION OF LUTEINIZING-HORMONE RELEASE IN STEROID-PRIMED OVARIECTOMIZED RATS
    ALLEN, LG
    CROWLEY, WR
    KALRA, SP
    [J]. ENDOCRINOLOGY, 1987, 121 (06) : 1953 - 1959
  • [10] NEUROPEPTIDE-Y DISTRIBUTION IN THE RAT-BRAIN
    ALLEN, YS
    ADRIAN, TE
    ALLEN, JM
    TATEMOTO, K
    CROW, TJ
    BLOOM, SR
    POLAK, JM
    [J]. SCIENCE, 1983, 221 (4613) : 877 - 879
12345678910